The purpose of this Funding Opportunity Announcement (FOA) is to solicit applications for the Nonhuman Primate Transplantation Tolerance Cooperative Study Group (NHPCSG), a multi-center, cooperative program dedicated to developing, optimizing, and evaluating approaches to induce and maintain immune tolerance to allogeneic transplants in nonhuman primate (NHP) models.
Donor Name: National Institutes of Health (NIH)
State: All States
County: All Counties
Type of Grant: Grant
Deadline (mm/dd/yyyy): 05/13/2022
Grant Size: $570,000
Grant Duration: 5 years
Details:
This FOA solicits applications from single institutions, or consortia of institutions, to participate in the Nonhuman Primate Transplantation Tolerance Cooperative Study Group (NHPCSG) program. The goals of the NHPCSG are to: (1) develop novel immune tolerance induction regimens; (2) evaluate the preclinical safety and efficacy of existing and newly developed candidate immune tolerance induction regimens; (3) develop and validate biomarkers for induction, maintenance and/or loss of immune tolerance or for prediction of graft rejection; and (4) elucidate mechanisms underlying induction, maintenance, and/or loss of tolerance in nonhuman primate (NHP) allograft models of kidney, pancreatic islet, heart, lung, liver, or intestinal transplantation.
The over-arching goal is to facilitate clinical translation of safe and effective tolerance-induction protocols for long-term graft survival.
Funding Information
- Application budgets are not limited but need to reflect the actual needs of the proposed project. As a guide, the approximate average direct costs for previous NHPCSG U01 awardees was $570,000, excluding the Infrastructure and Opportunities Fund.
- The maximum project period allowed is 5 years.
Eligibility Criteria
- Private institutions of higher education
- Independent school districts
- Public and State controlled institutions of higher education
- Native American tribal organizations (other than Federally recognized tribal governments)
- Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
- Special district governments
- Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
- State governments
- Public housing authorities/Indian housing authorities
- Native American tribal governments (Federally recognized)
- For profit organizations other than small businesses
- County governments
- Small businesses
- City or township governments
- Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
For more information, visit Grants.gov.